Mechanistic view of renal protective action of calcium channel blockade

Naoki Sugano, Koichi Hayashi, Tatsuo Hosoya, Takashi Yokoo

研究成果: Article

5 引用 (Scopus)

抜粋

Calcium channel blockers are one of the most useful antihypertensive agents because of their definite blood pressure lowering action. Although the antihypertensive effect of calcium channel blockers is attributed predominantly to the blockade of L-type calcium channels, recent studies demonstrate that the blockade of other subtypes of calcium channels, including T-type and N-type calcium channels, offers renal protective action because of their beneficial action on glomerular capillary pressure, renal fibrotic process, sympathetic nerve activity and aldosterone synthesis. It requires more extensive studies to clarify whether the ostensibly beneficial actions of these calcium channel blockers are available in a clinical setting.

元の言語English
ページ(範囲)187-192
ページ数6
ジャーナルCurrent Hypertension Reviews
9
発行部数3
DOI
出版物ステータスPublished - 2013

ASJC Scopus subject areas

  • Internal Medicine

フィンガープリント Mechanistic view of renal protective action of calcium channel blockade' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用