MEK inhibition preferentially suppresses anchorage-independent growth in osteosarcoma cells and decreases tumors in vivo

Takatsune Shimizu, Kiyomi Kimura, Eiji Sugihara, Sayaka Yamaguchi-Iwai, Hiroyuki Nobusue, Oltea Sampetrean, Yuji Otsuki, Yumi Fukuchi, Kaori Saitoh, Keiko Kato, Tomoyoshi Soga, Akihiro Muto, Hideyuki Saya