Melanin biosynthesis inhibitors from tarragon Artemisia dracunculus

Masayoshi Yamada, Kazuhiko Nakamura, Taeko Watabe, Osamu Ohno, Masaru Kawagoshi, Norihito Maru, Nobuo Uotsu, Tomohiro Chiba, Kohji Yamaguchi, Daisuke Uemura

研究成果: Article

7 引用 (Scopus)

抜粋

The EtOH extract of tarragon Artemisia dracunculus, a perennial herb in the family Asteraceae, was found to potently inhibit α-melanocyte-stimulating hormone (α-MSH) induced melanin production in B16 mouse melanoma cells. Bioassay-guided fractionation led to the isolation of two alkamide compounds, isobutyl (1) and piperidiyl (2) amides of undeca-2E,4E-dien-8,10- dynoic acid. The respective EC 50 values for melanin biosynthesis inhibition were 1.8 and 2.3μg/mL for 1 and 2.

元の言語English
ページ(範囲)1628-1630
ページ数3
ジャーナルBioscience, Biotechnology and Biochemistry
75
発行部数8
DOI
出版物ステータスPublished - 2011 8 29

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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  • これを引用

    Yamada, M., Nakamura, K., Watabe, T., Ohno, O., Kawagoshi, M., Maru, N., Uotsu, N., Chiba, T., Yamaguchi, K., & Uemura, D. (2011). Melanin biosynthesis inhibitors from tarragon Artemisia dracunculus. Bioscience, Biotechnology and Biochemistry, 75(8), 1628-1630. https://doi.org/10.1271/bbb.110306