抄録
The etiopathogenesis of extrahepatic manifestations including vasculitis in the context of HCV infection is still unknown. We report a case with lethal extrahepatic manifestations due to chronic hepatitis C virus (HCV) infection. The patient presented leukocytoclastic vasculitis, sensorimotor neuropathy and membranoproliferative glomerulonephritis with positive rheumatoid factor but lacked cryoglobulin. Hypocomplementaemia and deposition of IgM and C3 in the vascular lesion and glomeruli suggested that immune complex disease played a role in the pathogenesis of extrahepatic manifestations independent of cryoglobulin. Although HCV was successfully eliminated by treatment with interferon α, she died of cryptococcal infection.
本文言語 | English |
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ページ(範囲) | 1042-1046 |
ページ数 | 5 |
ジャーナル | Internal Medicine |
巻 | 42 |
号 | 10 |
DOI | |
出版ステータス | Published - 2003 10月 |
外部発表 | はい |
ASJC Scopus subject areas
- 内科学