TY - JOUR
T1 - Meroterpenoids from Penicillium citreo-viride B. IFO 4692 and 6200 hybrid
AU - Kosemura, Seiji
PY - 2003/6/30
Y1 - 2003/6/30
N2 - Twenty metabolites, citreohybridones, have been isolated from the mycelium of the hybrid strain KO 0031, prepared by cell fusion technique using Penicillium citreo-viride B. IFO 6200 and 4692. Their stereostructures have been elucidated on the basis of their spectral data and some chemical evidence, and their absolute configurations have been also elucidated by the modified Mosher's methods. Incorporation of 13C-labelled acetate, formate and ethyl 3,5-dimethylorsellinate into citreohybridones has established that their biosynthesis proceeds via a mixed polyketide-terpenoid (meroterpenoid) pathway.
AB - Twenty metabolites, citreohybridones, have been isolated from the mycelium of the hybrid strain KO 0031, prepared by cell fusion technique using Penicillium citreo-viride B. IFO 6200 and 4692. Their stereostructures have been elucidated on the basis of their spectral data and some chemical evidence, and their absolute configurations have been also elucidated by the modified Mosher's methods. Incorporation of 13C-labelled acetate, formate and ethyl 3,5-dimethylorsellinate into citreohybridones has established that their biosynthesis proceeds via a mixed polyketide-terpenoid (meroterpenoid) pathway.
KW - Absolute configuration
KW - Antifeedant
KW - Biosynthesis
KW - Citreohybridone
KW - Hybrid strain
KW - Meroterpenoid
KW - Penicillium citreo-viride B
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U2 - 10.1016/S0040-4020(03)00739-7
DO - 10.1016/S0040-4020(03)00739-7
M3 - Article
AN - SCOPUS:0038718473
VL - 59
SP - 5055
EP - 5072
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 27
ER -