Metabolic studies of galactosemic cataract

Hong Ming Cheng, Hua Xiong, Jing Xiong, Kazuo Tsubota

研究成果: Article

19 引用 (Scopus)

抜粋

Experimental diabetic and galactosemic animal models are widely used to study diabetes-induced complications. Galactose feeding can rapidly produce cataract, retinopathy and nephropathy; it is therefore favored over the diabetic model. Although the common feature for both models is the activation of aldose reductase, there are substantial differences between the two-not only does the rate of cataract progression differ but the metabolic patterns are far more complex than for polyol production alone. We here present the result of a comparison between diabetic and galactosemic lenses and show the differences in phosphorus and aldose metabolism, cell integrity and osmotic environment.

元の言語English
ページ(範囲)345-349
ページ数5
ジャーナルExperimental Eye Research
51
発行部数4
DOI
出版物ステータスPublished - 1990 10
外部発表Yes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

フィンガープリント Metabolic studies of galactosemic cataract' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用