抜粋
Here we present a new microfluidic platform that allows for the simultaneous imaging of cells migrating through a 3D matrix, production of a stable, concentration gradient of chemoattractant, and side-by-side comparisons of control and test conditions to normalize for sample-to-sample variability. We demonstrate the system here in a study of the migration of two tumor cell lines and the sprouting of endothelial cells into the matrix from a monolayer. We also show results using the same system to investigate the transmigration of a tumor cell across an endothelial monolayer. These experiments demonstrate the wide range of capabilities of the new system.
| 元の言語 | English |
|---|---|
| ページ | 24-26 |
| ページ数 | 3 |
| 出版物ステータス | Published - 2008 1 1 |
| 外部発表 | Yes |
| イベント | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States 継続期間: 2008 10 12 → 2008 10 16 |
Other
| Other | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 |
|---|---|
| 国 | United States |
| 市 | San Diego, CA |
| 期間 | 08/10/12 → 08/10/16 |
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering
フィンガープリント Microfluidic platform to study three dimensional cell migration & capillary morphogenesis' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。
これを引用
Chung, S., Sudo, R., Zervantonakis, I., Rimchala, T., Mack, P. J., Wan, C. R., Vickerman, V., & Kamm, R. D. (2008). Microfluidic platform to study three dimensional cell migration & capillary morphogenesis. 24-26. 論文発表場所 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.