Microinvasive Breast Carcinoma with Extensive Involvement of Level III Axillary Lymph Nodes: A Case Report

Kimihito Fujii, Takashi Fukutomi, Hitoshi Tsuda, Sadako Akashi-Tanaka, Takeshi Nanasawa, Yae Kanai, Yukio Muramatsu

研究成果: Article

2 引用 (Scopus)

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A 44-year-old woman presented with a right huge axillary mass. Both mammography and ultrasonography revealed a primary cancer of 2.8 cm maximum diameter in the right breast and metastases in the axillary lymph nodes, both being confirmed by aspiration cytology as ductal carcinoma. Right standard radical mastectomy with level III axillary lymph node dissection was carried out. Pathologically, the tumor was diagnosed as ductal carcinoma in situ with microinvasion (DCISM), histologic grade 3. The area of stromal invasion measured 1 mm at its widest point. Sixteen of the 17 resected axillary lymph nodes contained metastases, including six level III lymph nodes. Immunohistochemical studies of the tumor revealed overexpression of p53 protein, but not that of c-erbB-2 protein. The frequency of lymph node metastases from DCISM is reported to be very low. Therefore, the present case with extensive involvement of level III lymph nodes was unusual.

元の言語English
ページ(範囲)47-49
ページ数3
ジャーナルJapanese journal of clinical oncology
28
発行部数1
DOI
出版物ステータスPublished - 1998 1 1
外部発表Yes

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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