Microscale organization of chondrocyte array in hydrogel by dielectrophoresis

S. Miyata, Y. Takeuchi

研究成果: Conference contribution

抄録

Recently, microfabrication tools have been utilized to quantify the role of the cellular microenvironment on cell activity and function. Improving tissue regeneration by cell culture on scaffold material will also require tools to control cellular organization in 3-dimentional (3-D) condition. Our objective was to improve cartilage tissue engineering using 3-D cell organization technology. In this study, we developed an anisotropic cartilaginous tissue by cell patterning within hydrogel slabs using dielectrophoretic (DEP) forces. Our data indicate that the embedded chondrocytes remained viable and reconstructed cartilaginous tissue along the patterned cell array. DEP cell patterning may become a useful approach for reconstructing anisotropic structure in cartilage regeneration.

本文言語English
ホスト出版物のタイトルWorld Congress on Medical Physics and Biomedical Engineering
ホスト出版物のサブタイトルMicro- and Nanosystems in Medicine, Active Implants, Biosensors
出版社Springer Verlag
ページ233-234
ページ数2
8
ISBN(印刷版)9783642038860
DOI
出版ステータスPublished - 2009
イベントWorld Congress on Medical Physics and Biomedical Engineering: Micro- and Nanosystems in Medicine, Active Implants, Biosensors - Munich, Germany
継続期間: 2009 9月 72009 9月 12

出版物シリーズ

名前IFMBE Proceedings
番号8
25
ISSN(印刷版)1680-0737

Other

OtherWorld Congress on Medical Physics and Biomedical Engineering: Micro- and Nanosystems in Medicine, Active Implants, Biosensors
国/地域Germany
CityMunich
Period09/9/709/9/12

ASJC Scopus subject areas

  • バイオエンジニアリング
  • 生体医工学

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