Modeling Familial Parkinson's Disease Using Patient-specific Induced Pluripotent Stem Cells

Yoshikuni Tabata, Hideyuki Okano

研究成果: Review article査読

抄録

Parkinson's disease (PD), a common neurodegenerative disorder, is characterized by selective degeneration of dopaminergic neurons in the substantia nigra. There is no effective treatment to delay or halt the progression of PD. The establishment of disease models, based on human biology, is therefore important for developing effective disease-modifying therapies. The recent progress of human induced pluripotent stem cell-associated technologies provides an opportunity to understand disease etiology, discover new drugs, and develop novel therapeutic interventions.

本文言語English
ページ(範囲)875-883
ページ数9
ジャーナルBrain and nerve = Shinkei kenkyu no shinpo
71
8
DOI
出版ステータスPublished - 2019 8 1

ASJC Scopus subject areas

  • 臨床神経学

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