Modified ultrafiltration improves carbon dioxide removal after cardiopulmonary bypass in infants

Ryo Aeba, Toshiyuki Katogi, Tadashi Omoto, Ichiro Kashima, Shiaki Kawada

研究成果: Article査読

14 被引用数 (Scopus)

抄録

Little is known about the role of modified ultrafiltration in ameliorating the adverse effects of the cardiopulmonary bypass on pulmonary function in infants. Twenty-nine nonrandomized consecutive infants (<12 months of age) who underwent unrestrictive ventricular septal defect closure between 1995 and 1998 were included in this study. Down's syndrome was associated in 9 patients. The actual ventilator settings were highly homogeneous among all patients and each time point in the study. Fourteen infants received modified ultrafiltration after the discontinuation of cardiopulmonary bypass. Fifteen un- treated patients served as the control group. Correlates of cardiac and pulmonary functions for both groups were compared. The arterial carbon dioxide tension in the experimental group was significantly lower than in the control group from 20 to 240 min after bypass. Arterial oxygenation and pulmonary arterial pressure were similar in the 2 groups. Modified ultrafiltration improves carbon dioxide removal after cardiopulmonary bypass in infants. This may potentially convey a beneficial impact on hemodynamics.

本文言語English
ページ(範囲)300-304
ページ数5
ジャーナルArtificial Organs
24
4
DOI
出版ステータスPublished - 2000
外部発表はい

ASJC Scopus subject areas

  • バイオエンジニアリング
  • 医学(その他)
  • 生体材料
  • 生体医工学

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