Molecular cloning of ϕ80 adsorption-inhibiting cor gene

Midori Matsumoto, Takashi Morita, Aizo Matsushiro, Norio Ichikawa, Shigeo Tanaka

研究成果: Article査読

12 被引用数 (Scopus)

抄録

It was reported that ϕ80 lysogens did not adsorb superinfecting phage ϕ80 and a gene responsible to the phenomenon was named cor (Kozyrev et al., 1982). We found that E. coli containing ϕ80 genome in lytic cycle also began to show resistance to superinfecting ϕ80 after 5 min of infection. We cloned the cor gene and determined its nucleotide sequence. A putative cor gene product should be 92 amino acids long and have three hydrophobic cores and one hydrophilic region, indicating a possibility of membrane binding protein. The product may interact with ϕ80 receptor on inner- or outer-membrane of E. coli cells and inhibit the adsorption of superinfecting ϕ80. The cor gene is supposed to be transcribed from a unique promoter located close to the gene.

本文言語English
ページ(範囲)475-483
ページ数9
ジャーナルThe Japanese Journal of Genetics
60
5
DOI
出版ステータスPublished - 1985
外部発表はい

ASJC Scopus subject areas

  • Genetics

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