Molecular cloning of a full-length cDNA encoding the catalytic subunit of human calmodulin-dependent protein phosphatase (calcineurin Aα)

Taro Muramatsu, Randall L. Kincaid

研究成果: Article査読

31 被引用数 (Scopus)

抄録

A complementary DNA for human calcineurin Aα (protein phosphatase-2B), encoding a protein of 521 amino acids, was isolated from a hippocampus library. The deduced human sequence differs from that of mouse in only two amino acids, demonstrating that the structure of this catalytic subunit has been strictly conserved during mammalian evolution. Such high homology is in contrast to that seen for calcineurin Aγ, an isoform that shows only 88% identity between human and mouse (Muramatsu, T. and Kincaid, R.L. (1992) Biochem. Biophys. Res. Commun. 188, 265-271).

本文言語English
ページ(範囲)117-120
ページ数4
ジャーナルBBA - Molecular Cell Research
1178
1
DOI
出版ステータスPublished - 1993 7月 28
外部発表はい

ASJC Scopus subject areas

  • 分子生物学
  • 細胞生物学

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