Molecular dynamics study on structual change in the surface membrane of an insonified coated microbubble

F. Ueki, S. Ito, Kazuaki Takahashi, K. Yasuoka, T. Sugiura

研究成果: Conference contribution

抄録

Coated microbubbles used as ultrasound contrast agents show complicated nonlinear oscillation if insonified. The Marmottant model assumes the experimental surface tension that changes with the bubble radius. Though this model has been widely used in recent years, its physical background is still unclear. In this work, we focused on the molecular level state of the membrane of a coated microbubbles and performed molecular dynamics (MD) simulations of a water-membrane-gas interfacial system. For efficient calculations, the Coarse-Grained (CG) model was used. In this model, the group of atoms is replaced by one effective particle. The calculation efficiency is greatly improved, because the computational cost for interaction calculations is proportional to the power of the number of particles. We obtained stable structures of amphiphilic membrane molecules at different membrane surface densities that are related to the bubble size. The results of membrane thicknesses show qualitative change of the membrane state, and imply the possibility of the phase transition.

本文言語English
ホスト出版物のタイトル2012 IEEE International Ultrasonics Symposium, IUS 2012
ページ2282-2285
ページ数4
DOI
出版ステータスPublished - 2012 12 1
イベント2012 IEEE International Ultrasonics Symposium, IUS 2012 - Dresden, Germany
継続期間: 2012 10 72012 10 10

出版物シリーズ

名前IEEE International Ultrasonics Symposium, IUS
ISSN(印刷版)1948-5719
ISSN(電子版)1948-5727

Other

Other2012 IEEE International Ultrasonics Symposium, IUS 2012
国/地域Germany
CityDresden
Period12/10/712/10/10

ASJC Scopus subject areas

  • 音響学および超音波学

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