Molecular mechanisms underlying the effects of sex steroids on bone and mineral metabolism

Yuuki Imai, Takashi Nakamura, Takahiro Matsumoto, Kunio Takaoka, Shigeaki Kato

研究成果: Review article査読

11 被引用数 (Scopus)

抄録

The multifarious functions of sex steroid receptors include a role as regulatory factors for bone and mineral metabolism in vivo. These functions are more complex than originally assumed. The finding of nuclear receptors in osseous tissue alludes to the existence of novel indirect and direct functions of bone tissue beyond skeletal support, hematopoiesis, and calcium homeostasis. Cell-specific gene targeting approaches are an extremely important technology for future studies that will need to be conducted to fully understand the molecular mechanisms underlying bone formation and metabolism.

本文言語English
ページ(範囲)127-130
ページ数4
ジャーナルJournal of Bone and Mineral Metabolism
27
2
DOI
出版ステータスPublished - 2009 3
外部発表はい

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine

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