TY - JOUR

T1 - Monte Carlo analysis of near-infrared light propagation in a neonatal head model

AU - Eda, Shuhei

AU - Okada, Eiji

PY - 2004/8/1

Y1 - 2004/8/1

N2 - In brain function measurement using near-infrared light, it is very important to make a theoretical analysis of light propagation in the head tissue, since it is impossible to measure the effect of optical fiber arrangement on the region of measurement or its sensitivity. The Monte Carlo method is widely used in the analysis of near-infrared light propagation in biological tissue, since it allows light propagation analysis of heterogeneous tissue by a relatively simple algorithm. In this study, a model simulating the cross-sectional structure of the neonatal head is constructed by using square elements, and the light propagation is analyzed. First, the variance-reduction (VR) method and the delta-scattering (DS) method, which are typical algorithms of the Monte Carlo method, are applied to the model composed of square elements, and the results of the analysis and the computation time for light propagation are compared and discussed. It is shown that the DS method is useful for a model composed of small square elements, since the computation time depends little on the size of the elements. As a result of analysis of light propagation in the neonatal head model using the DS method, we see that light propagation is greatly affected by the heterogeneity of the head tissue.

AB - In brain function measurement using near-infrared light, it is very important to make a theoretical analysis of light propagation in the head tissue, since it is impossible to measure the effect of optical fiber arrangement on the region of measurement or its sensitivity. The Monte Carlo method is widely used in the analysis of near-infrared light propagation in biological tissue, since it allows light propagation analysis of heterogeneous tissue by a relatively simple algorithm. In this study, a model simulating the cross-sectional structure of the neonatal head is constructed by using square elements, and the light propagation is analyzed. First, the variance-reduction (VR) method and the delta-scattering (DS) method, which are typical algorithms of the Monte Carlo method, are applied to the model composed of square elements, and the results of the analysis and the computation time for light propagation are compared and discussed. It is shown that the DS method is useful for a model composed of small square elements, since the computation time depends little on the size of the elements. As a result of analysis of light propagation in the neonatal head model using the DS method, we see that light propagation is greatly affected by the heterogeneity of the head tissue.

KW - Brain function measurement

KW - Light propagation analysis

KW - Monte Carlo method

KW - Near-infrared spectroscopy

UR - http://www.scopus.com/inward/record.url?scp=4444264864&partnerID=8YFLogxK

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U2 - 10.1002/scj.10246

DO - 10.1002/scj.10246

M3 - Article

AN - SCOPUS:4444264864

VL - 35

SP - 60

EP - 69

JO - Systems and Computers in Japan

JF - Systems and Computers in Japan

SN - 0882-1666

IS - 9

ER -