TY - JOUR
T1 - Monte Carlo simulation of characteristics of OCT signal from the boundary of optical property mismatch
AU - Hojo, Masaki
AU - Okada, Eiji
PY - 2003/12/1
Y1 - 2003/12/1
N2 - The optical coherence tomography (OCT) has been successfully applied to diagnostic imaging of transparent ocular organs. In case of highly scattering tissues such as skin and mucous membrane, and the OCT signal includes noise component due to multiple scattering in tissue, the characteristics of the OCT signal from the highly scattering tissue is more complex. In this study, we investigate the characteristics of the OCT signal from the low-scattering and highly scattering tissues by Monte Carlo simulation. In case of low-scattering tissue, the intensity of the signal is maximised when the focal depth equals the probing depth and the spurious peak of the noise due to scattering is observed at the focal depth in the OCT image. In case of highly scattering tissue, the intensity of the signal is maximised when the focal depth is smaller than the probing depth and the noise is almost independent of the focal depth.
AB - The optical coherence tomography (OCT) has been successfully applied to diagnostic imaging of transparent ocular organs. In case of highly scattering tissues such as skin and mucous membrane, and the OCT signal includes noise component due to multiple scattering in tissue, the characteristics of the OCT signal from the highly scattering tissue is more complex. In this study, we investigate the characteristics of the OCT signal from the low-scattering and highly scattering tissues by Monte Carlo simulation. In case of low-scattering tissue, the intensity of the signal is maximised when the focal depth equals the probing depth and the spurious peak of the noise due to scattering is observed at the focal depth in the OCT image. In case of highly scattering tissue, the intensity of the signal is maximised when the focal depth is smaller than the probing depth and the noise is almost independent of the focal depth.
KW - Optical coherence tomography
KW - Optical property mismatch
KW - Photon migration in tissue
UR - http://www.scopus.com/inward/record.url?scp=1342268067&partnerID=8YFLogxK
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M3 - Conference article
AN - SCOPUS:1342268067
SN - 0277-786X
VL - 5138
SP - 190
EP - 197
JO - Proceedings of SPIE - The International Society for Optical Engineering
JF - Proceedings of SPIE - The International Society for Optical Engineering
T2 - Photon Migration and Diffuse-Light Imaging
Y2 - 22 June 2003 through 23 June 2003
ER -