MPAI (Mass Probes Aided Ionization) method for total analysis of biomolecules by mass spectrometry

Aki Honda, Shinichiro Hayashi, Hiroki Hifumi, Yuya Honma, Noriyuki Tanji, Naoko Iwasawa, Yoshio Suzuki, Koji Suzuki

研究成果: Review article査読

14 被引用数 (Scopus)

抄録

We have designed and synthesized various mass probes, which enable us to effectively ionize various molecules to be detected with mass spectrometry. We call the ionization method using mass probes the "MPAI (mass probes aided ionization)" method. We aim at the sensitive detection of various biological molecules, and also the detection of biomolecules by a single mass spectrometry serially without changing the mechanical settings. Here, we review mass probes for small molecules with various functional groups and mass probes for proteins. Further, we introduce newly developed mass probes for proteins for highly sensitive detection. 2007

本文言語English
ページ(範囲)11-15
ページ数5
ジャーナルanalytical sciences
23
1
DOI
出版ステータスPublished - 2007 1

ASJC Scopus subject areas

  • 分析化学

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