@article{cc4233969e5944a7ad4a5088e70c5dd5,
title = "Multicenter observational cohort study of post-operative treatment for completely resected non-small-cell lung cancer of pathological Stage I (T1 >2 cm and T2 in TNM classification version 6)",
abstract = "Post-operative adjuvant chemotherapy has been considered an effective strategy to reduce cancer recurrence and improve survival for resected non-small-cell lung cancer. The Japan Clinical Oncology Group has completed patient accrual for a randomized Phase III study (JCOG0707), which compares the survival benefit of UFT and S-1 for completely resected pathological Stage I (T1 >2 cm and T2 in TNM classification version 6) non-small-cell lung cancer. However, there is a growing concern that those who participated in clinical trials are highly selected patients and do not represent the 'realworld' population. This multicenter observational cohort study aims to analyze the backgrounds, pattern of care and outcomes of the patients who were excluded from the JCOG0707 study during the accrual period. The results of this cohort study will be useful for external validity of the results of clinical trial such as JCOG0707.",
keywords = "Early stage, Non-small-cell lung cancer, Observational cohort study, Post-operative adjuvant chemotherapy, Randomized Phase III study",
author = "Tomoyuki Hishida and Masahiro Tsuboi and Takehito Shukuya and Kazuya Takamochi and Hiroyuki Sakurai and Kiyotaka Yoh and Yasuo Ohashi and Hideo Kunitoh",
note = "Funding Information: This study is sponsored by the Comprehensive Support Project for Oncology Research (CSPOR) of Public Health Research Foundation. However, the funds for Study A are provided by Taiho Pharmaceutical Co., Ltd. according to a contract. The secretary for the CSPOR will perform the clerical work for the study but will not make decisions in association with planning, implementation, and publication of the study. Additionally, this study will be administered independent of the provider of the funds, and the provider of the funds will never be involved in the decision making for the planning, implementation, analysis and publication of the study. The decisions regarding the planning, implementation, and publication of the study will be made by the executive committee for the study. Publisher Copyright: {\textcopyright} The Author 2015. Published by Oxford University Press. All rights reserved.",
year = "2015",
month = may,
day = "1",
doi = "10.1093/jjco/hyv028",
language = "English",
volume = "45",
pages = "499--501",
journal = "Japanese Journal of Clinical Oncology",
issn = "0368-2811",
publisher = "Oxford University Press",
number = "5",
}
