Multilectin-assisted fractionation for improved single-dot tissue glycome profiling in clinical glycoproteomics

Binbin Tan, Atsushi Matsuda, Yan Zhang, Atsushi Kuno, Hisashi Narimatsu

研究成果: Article

5 引用 (Scopus)

抄録

To survey the glycome shift in cancer, single-dot tissue glycome profiling was improved by incorporating a lectin-assisted fractionation. The differential analysis of tissue specimens from colorectal cancer patients (n = 45) revealed that unfucosylated/α2,6-sialylated glycoproteins significantly increased in patients with poor prognoses. The detailed annotation will be an indispensable supplement for cancer-related glyco-biomarker discovery.

元の言語English
ページ(範囲)201-205
ページ数5
ジャーナルMolecular BioSystems
10
発行部数2
DOI
出版物ステータスPublished - 2014 2
外部発表Yes

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Lectins
Colorectal Neoplasms
Neoplasms
Glycoproteins
Biomarkers
Surveys and Questionnaires

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Biology

これを引用

Multilectin-assisted fractionation for improved single-dot tissue glycome profiling in clinical glycoproteomics. / Tan, Binbin; Matsuda, Atsushi; Zhang, Yan; Kuno, Atsushi; Narimatsu, Hisashi.

:: Molecular BioSystems, 巻 10, 番号 2, 02.2014, p. 201-205.

研究成果: Article

Tan, Binbin ; Matsuda, Atsushi ; Zhang, Yan ; Kuno, Atsushi ; Narimatsu, Hisashi. / Multilectin-assisted fractionation for improved single-dot tissue glycome profiling in clinical glycoproteomics. :: Molecular BioSystems. 2014 ; 巻 10, 番号 2. pp. 201-205.
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