Multiple perivascular epithelioid cell tumors: Clear cell tumor of the lung accompanied by angiomyolipoma of the liver

Shinya Neri, Genichiro Ishii, Keiju Aokage, Tomoyuki Hishida, Junji Yoshida, Mitsuyo Nishimura, Kanji Nagai

研究成果: Article査読

3 被引用数 (Scopus)

抄録

Clear cell tumor (CCT) of the lung is very rare, and angiomyolipoma (AML) of the liver is also very rare. Both CCT and AML have been identified as a group of neoplasms with perivascular epithelioid cell differentiation (PEComa). We report a case with multiple PEComas of a combination of CCT of the lung and AML of the liver. The patient underwent surgical resection of an abnormal nodule of the lung 5 years after treatment of AML of the liver. The histological diagnosis of the pulmonary nodule was CCT. Neither lesion demonstrated malignant phenotypes, such as high mitotic activity, necrosis, or lymphovascular invasion. Each tumor of the lung and liver was solitary and differed from each other histologically. Therefore, these tumors were considered to be multifocal, not metastatic PEComas. This case is, to our knowledge, the first report of multiple PEComas of pulmonary CCT and hepatic AML. These findings suggest that patients with PEComas may require whole-body follow-up examinations because different subtypes of PEComas may occur multifocally.

本文言語English
ページ(範囲)453-456
ページ数4
ジャーナルAnnals of Thoracic and Cardiovascular Surgery
20
DOI
出版ステータスPublished - 2014
外部発表はい

ASJC Scopus subject areas

  • 外科
  • 呼吸器内科
  • 循環器および心血管医学
  • 消化器病学

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