Myofibroblasts in fibrous tumors and fibrosis in various organs

I. Nakanishi, K. Kajikawa, Y. Okada, K. Eguchi

研究成果: Article査読

19 被引用数 (Scopus)


The morphology and population of myofibroblasts detected by electron microscopy in fibrous tumors and fibrosis in various organs have been examined. The myofibroblast was identified by characteristic features of the indented nucleus, bundles of abundant microfilaments with dense bodies, focal basal lamina and well-developed rough endoplasmic reticulum. It has been observed that myofibroblasts in a variety of fibrous tumors and fibrosis appeared predominantly in fibromatosis and reparative process of deep fibrous tissues and organs particularly in the lesions involving the fascia and subcutaneous tissue. It was suggested that myofibroblasts would be modified fibroblasts to which fibroblasts in the fascia and deeply situated fibrous tissue transformed during proliferation and differentiation.

ジャーナルActa Pathologica Japonica
出版ステータスPublished - 1981

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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