Natural compounds with Wnt signal modulating activity

Rolly G. Fuentes, Midori A. Arai, Masami Ishibashi

研究成果: Review article査読

32 被引用数 (Scopus)

抄録

Covering: up to 2015 The Wnt signalling pathway is essential in many biological processes. The Wnt signal is associated with several diseases, particularly cancer and neurodegenerative diseases. Recently, high-throughput screening systems have been developed to rapidly identify compounds, including natural compounds, that target the Wnt signal. Some studies on natural modulators of the Wnt signal have also suggested their possible target. This review highlights some important natural compounds reported to regulate Wnt activity and describes their possible mechanism of action.

本文言語English
ページ(範囲)1622-1628
ページ数7
ジャーナルNatural Product Reports
32
12
DOI
出版ステータスPublished - 2015 12月
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

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