Newly developed fusogenic liposome

J. Sunamoto, K. Akiyoshi, K. Tanaka, T. Sato

研究成果: Conference article査読

11 被引用数 (Scopus)

抄録

Liposome has been widely utilized as a vehicle for delivering various substances such as DNA, RNA, enzymes, proteins, metabolites, or pharmaceutical drugs into various cells. For internalization of liposomes into cells, two possible paths have been considered; namely, phagocytosis (or endocytosis) and fusion. However, all previous methods still have several disadvantages. In order to overcome these disadvantages, we have designed a fusogenic liposome as prepared by mixing simple egg phosphatidylchloline and an artificial lipid, 2-[ω-hydroxy(oxyethylene)-α-yl]-1,3-bis-(dodecyloxy) propane and investigated the fusion between the fusogenic liposomes and carrot protoplasts.

本文言語English
ページ(範囲)155-156
ページ数2
ジャーナルAmerican Chemical Society, Polymer Preprints, Division of Polymer Chemistry
31
2
出版ステータスPublished - 1990 8月 1
外部発表はい
イベントPapers presented at the Washington, DC Meeting 1990 of the ACS, Division of Polymer Chemistry - Washington, DC, USA
継続期間: 1990 8月 261990 8月 31

ASJC Scopus subject areas

  • 材料科学(全般)
  • ポリマーおよびプラスチック
  • 工学(全般)

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