Non-Cell-Autonomous Neurotoxicity in Parkinson's Disease Mediated by Astroglial α-Synuclein

Muh Chyi Chai; Jun Kohyama

doi:10.1016/j.stemcr.2019.01.011

Non-Cell-Autonomous Neurotoxicity in Parkinson's Disease Mediated by Astroglial α-Synuclein

Muh Chyi Chai, Jun Kohyama

生理学

研究成果: Short survey

2 被引用数 (Scopus)

抄録

Non-cell-autonomous effects on neuronal cells are considered to be involved in the pathogenesis of neurodegenerative diseases but have yet to be mechanistically proven. In this issue of Stem Cell Reports, di Domenico et al. provide direct evidence that α-synuclein transferred from astrocytes exerts non-cell-autonomous neuronal dysfunction on dopaminergic neurons in Parkinson's disease (PD).

本文言語	English
ページ（範囲）	183-185
ページ数	3
ジャーナル	Stem cell reports
巻	12
号	2
DOI	https://doi.org/10.1016/j.stemcr.2019.01.011
出版ステータス	Published - 2019 2 12

ASJC Scopus subject areas

Biochemistry
Genetics
Developmental Biology
Cell Biology

文献へのアクセス

10.1016/j.stemcr.2019.01.011

フィンガープリント「Non-Cell-Autonomous Neurotoxicity in Parkinson's Disease Mediated by Astroglial α-Synuclein」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル

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