Novel aromatic substances, dictyomedin A and B, from Dictyostelium cellular slime molds and their inhibitory effects on Dictyostelium development

Yoshiaki Takaya, Haruhisa Kikuchi, Yuichi Terui, Jun Komiya, Yasuo Maeda, Akira Ito, Yoshiteru Oshima

研究成果: Article査読

26 被引用数 (Scopus)

抄録

To elucidate the diversity of secondary metabolites of Dictyostelium cellular slime molds and search for physiologically active substances affecting their development, we investigated the constituents of D. medium. From the methanol extract of its fruit body, we obtained two novel aromatic compounds named dictyomedin A (1) and B (2), and their structures were elucidated by means of physicochemical data. Biological evaluation of the compounds showed that they delayed the differentiation of D. discoideum cells.

本文言語English
ページ(範囲)61-63
ページ数3
ジャーナルTetrahedron Letters
42
1
DOI
出版ステータスPublished - 2001 1 1
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

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