Novel mainstream capnometer system is safe and feasible even under CO 2 insufflation during ERCP-related procedure: A pilot study

Yoichi Takimoto, Eisuke Iwasaki, Tatsuhiro Masaoka, Seiichiro Fukuhara, Shintaro Kawasaki, Takashi Seino, Tadashi Katayama, Kazuhiro Minami, Hiroki Tamagawa, Yujiro Machida, Haruhiko Ogata, Takanori Kanai

研究成果: Article

抄録

Background and aims There is a need to safely achieve conscious sedation during endoscopic retrograde cholangiopancreatography (ERCP). We evaluated the safety and feasibility of a mainstream capnometer system to monitor apnoea during ERCP under CO 2 insufflation. Methods Non-intubated adult patients undergoing ERCP-related procedures with intravenous sedation were enrolled. End-tidal CO 2 (EtCO 2 ) was continuously monitored during the procedure under CO 2 insufflation using a mainstream capnometer system, comprising a capnometer and a specially designed bite block for upper gastrointestinal endoscopy and ERCP. Oxygen saturation (SpO 2) was also monitored continuously during the procedure. In this study, we evaluated the safety and feasibility of the capnometer system. Results Eleven patients were enrolled. Measurement of EtCO 2 concentration was possible from the beginning to the end of the procedure in all 11 cases. There was no measurement failure, dislocation of the bite block, or adverse event related to the bite block. Apnoea linked to hypoxaemia occurred five times (mean duration, 174.4 s). Conclusion This study confirmed that apnoea was detected earlier than when using a percutaneous oxygen monitor. Measurement of EtCO 2 concentration using the newly developed mainstream capnometer system was feasible and safe even under CO 2 insufflation.

元の言語English
記事番号e000266
ジャーナルBMJ Open Gastroenterology
6
発行部数1
DOI
出版物ステータスPublished - 2019 2 1

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Insufflation
Endoscopic Retrograde Cholangiopancreatography
Carbon Monoxide
Apnea
Bites and Stings
Oxygen
Conscious Sedation
Safety
Gastrointestinal Endoscopy

ASJC Scopus subject areas

  • Gastroenterology

これを引用

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title = "Novel mainstream capnometer system is safe and feasible even under CO 2 insufflation during ERCP-related procedure: A pilot study",
abstract = "Background and aims There is a need to safely achieve conscious sedation during endoscopic retrograde cholangiopancreatography (ERCP). We evaluated the safety and feasibility of a mainstream capnometer system to monitor apnoea during ERCP under CO 2 insufflation. Methods Non-intubated adult patients undergoing ERCP-related procedures with intravenous sedation were enrolled. End-tidal CO 2 (EtCO 2 ) was continuously monitored during the procedure under CO 2 insufflation using a mainstream capnometer system, comprising a capnometer and a specially designed bite block for upper gastrointestinal endoscopy and ERCP. Oxygen saturation (SpO 2) was also monitored continuously during the procedure. In this study, we evaluated the safety and feasibility of the capnometer system. Results Eleven patients were enrolled. Measurement of EtCO 2 concentration was possible from the beginning to the end of the procedure in all 11 cases. There was no measurement failure, dislocation of the bite block, or adverse event related to the bite block. Apnoea linked to hypoxaemia occurred five times (mean duration, 174.4 s). Conclusion This study confirmed that apnoea was detected earlier than when using a percutaneous oxygen monitor. Measurement of EtCO 2 concentration using the newly developed mainstream capnometer system was feasible and safe even under CO 2 insufflation.",
keywords = "end-tidal carbon dioxide (EtCO ), endoscopic retrograde cholangiopancreatography (ERCP), endoscopic ultrasound (EUS)",
author = "Yoichi Takimoto and Eisuke Iwasaki and Tatsuhiro Masaoka and Seiichiro Fukuhara and Shintaro Kawasaki and Takashi Seino and Tadashi Katayama and Kazuhiro Minami and Hiroki Tamagawa and Yujiro Machida and Haruhiko Ogata and Takanori Kanai",
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language = "English",
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T1 - Novel mainstream capnometer system is safe and feasible even under CO 2 insufflation during ERCP-related procedure

T2 - A pilot study

AU - Takimoto, Yoichi

AU - Iwasaki, Eisuke

AU - Masaoka, Tatsuhiro

AU - Fukuhara, Seiichiro

AU - Kawasaki, Shintaro

AU - Seino, Takashi

AU - Katayama, Tadashi

AU - Minami, Kazuhiro

AU - Tamagawa, Hiroki

AU - Machida, Yujiro

AU - Ogata, Haruhiko

AU - Kanai, Takanori

PY - 2019/2/1

Y1 - 2019/2/1

N2 - Background and aims There is a need to safely achieve conscious sedation during endoscopic retrograde cholangiopancreatography (ERCP). We evaluated the safety and feasibility of a mainstream capnometer system to monitor apnoea during ERCP under CO 2 insufflation. Methods Non-intubated adult patients undergoing ERCP-related procedures with intravenous sedation were enrolled. End-tidal CO 2 (EtCO 2 ) was continuously monitored during the procedure under CO 2 insufflation using a mainstream capnometer system, comprising a capnometer and a specially designed bite block for upper gastrointestinal endoscopy and ERCP. Oxygen saturation (SpO 2) was also monitored continuously during the procedure. In this study, we evaluated the safety and feasibility of the capnometer system. Results Eleven patients were enrolled. Measurement of EtCO 2 concentration was possible from the beginning to the end of the procedure in all 11 cases. There was no measurement failure, dislocation of the bite block, or adverse event related to the bite block. Apnoea linked to hypoxaemia occurred five times (mean duration, 174.4 s). Conclusion This study confirmed that apnoea was detected earlier than when using a percutaneous oxygen monitor. Measurement of EtCO 2 concentration using the newly developed mainstream capnometer system was feasible and safe even under CO 2 insufflation.

AB - Background and aims There is a need to safely achieve conscious sedation during endoscopic retrograde cholangiopancreatography (ERCP). We evaluated the safety and feasibility of a mainstream capnometer system to monitor apnoea during ERCP under CO 2 insufflation. Methods Non-intubated adult patients undergoing ERCP-related procedures with intravenous sedation were enrolled. End-tidal CO 2 (EtCO 2 ) was continuously monitored during the procedure under CO 2 insufflation using a mainstream capnometer system, comprising a capnometer and a specially designed bite block for upper gastrointestinal endoscopy and ERCP. Oxygen saturation (SpO 2) was also monitored continuously during the procedure. In this study, we evaluated the safety and feasibility of the capnometer system. Results Eleven patients were enrolled. Measurement of EtCO 2 concentration was possible from the beginning to the end of the procedure in all 11 cases. There was no measurement failure, dislocation of the bite block, or adverse event related to the bite block. Apnoea linked to hypoxaemia occurred five times (mean duration, 174.4 s). Conclusion This study confirmed that apnoea was detected earlier than when using a percutaneous oxygen monitor. Measurement of EtCO 2 concentration using the newly developed mainstream capnometer system was feasible and safe even under CO 2 insufflation.

KW - end-tidal carbon dioxide (EtCO )

KW - endoscopic retrograde cholangiopancreatography (ERCP)

KW - endoscopic ultrasound (EUS)

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