Novel method of tetramic acid synthesis: Silver-catalyzed carbon dioxide incorporation into propargylic amine and intramolecular rearrangement

Tomonobu Ishida, Ryo Kobayashi, Tohru Yamada

研究成果: Article査読

68 被引用数 (Scopus)

抄録

Tetramic acid derivatives have been studied as biologically active heterocycle structures for pharmaceutical or agricultural chemicals. Conventional preparative approaches often require highly functionalized starting materials and harsh heating conditions in basic media. The present report provides a conceptually new synthetic strategy for the synthesis of tetramic acid derivatives from easily available propargylic amines and carbon dioxide with a silver salt and DBU under mild reaction conditions.

本文言語English
ページ(範囲)2430-2433
ページ数4
ジャーナルOrganic Letters
16
9
DOI
出版ステータスPublished - 2014 5月 2

ASJC Scopus subject areas

  • 生化学
  • 物理化学および理論化学
  • 有機化学

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