Novel short-duration heating balloon dilatation with uniform temperature distribution: The heating conditions to suppress neo-intimal hyperplasia

M. Kunio, N. Shimazaki, T. Arai, M. Sakurada

研究成果: Conference contribution

抄録

We investigate the relation between the influences on smooth muscle cells and the chronic performances of our novel short-duration heating balloon dilatation to reveal the heating conditions which can suppress the neo-intimal hyperplasia after our heating dilatations. The temperature of prototype balloon catheter surface was measured during short-duration heating balloon dilatation ex vivo. There existed 2C temperature variations in the long direction of prototype balloon catheter at a maximum. The neo-intimal hyperplasia occupancy rate after our short-duration heating dilatations were measured in vivo porcine study. The neo-intimal hyperplasia was suppressed most at 75C in balloon peak temperature in vivo. The estimated dead rate of smooth muscle cells at this condition was about 13% by the Arrhenius equation. We think that the suppression of neo-intimal hyperplasia was obtained after our short-duration heating dilatation due to the proper decrease of smooth muscle cells by heating and no thermal damages to the adventitia and surrounding tissues.

本文言語English
ホスト出版物のタイトル33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
ページ349-352
ページ数4
DOI
出版ステータスPublished - 2011
外部発表はい
イベント33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, United States
継続期間: 2011 8月 302011 9月 3

出版物シリーズ

名前Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN(印刷版)1557-170X

Other

Other33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
国/地域United States
CityBoston, MA
Period11/8/3011/9/3

ASJC Scopus subject areas

  • 信号処理
  • 生体医工学
  • コンピュータ ビジョンおよびパターン認識
  • 健康情報学

フィンガープリント

「Novel short-duration heating balloon dilatation with uniform temperature distribution: The heating conditions to suppress neo-intimal hyperplasia」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル