Numerical simulation of near-field fluorescence correlation spectroscopy using a fiber probe

Kazuo Kasahara, Toshiharu Saiki

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Numerical simulation of fluorescence correlation spectroscopy (FCS) based on near-field scanning optical microscopy (NSOM) was performed. A finite-difference time-domain method was employed to calculate the electric field distribution in the vicinity of the NSOM aperture and the Brownian motion of nanoparticles was reproduced by a Monte Carlo simulation. The physical validity of the simulation result was confirmed by comparing it with a theoretical calculation using a Gaussian observation volume, which is applied to FCS based on conventional optical microscopy.

本文言語English
論文番号043502
ジャーナルJournal of Nanophotonics
4
1
DOI
出版ステータスPublished - 2010

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

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