Observation of transformation behavior of octacalcium phosphate to hydroxyapatite

Natsuko Ito, Masanobu Kamitakahara, Koji Ioku

研究成果: Conference contribution

2 被引用数 (Scopus)

抄録

Octacalcium phosphate (OCP) is regarded as a precursor of hydroxyapatite (HA) which is a main inorganic comstituent of human bones and teeth. OCP is becoming regarded as an important biomaterial. Recently, implanted OCP was found to be converted to apatitic phase in the body and support bone regeneration. Therefore, it is important to reveal the transformation mechanism of OCP to HA for revealing the mechanism of bone formation and for the development of biomedical materials for bone. In this study, we focused on the dissolution of OCP and precipitation of HA. OCP particles were immersed in distilled water at 60 ?C. The temporal change of the immersed powders and immersing solution were examined, and the transformation mechanism of OCP to HA was discussed. As there was an unreactive period in the first stage of the transformation, HA crystals seemed to grow easily once HA nuclei were formed. It is speculated that HA nuclei formed on OCP crystals by heterogeneous nucleation, and then HA crystals grow using calcium and phosphoric ions supplied from dissolved OCP.

本文言語English
ホスト出版物のタイトルBioceramics 24
出版社Trans Tech Publications Ltd
ページ11-14
ページ数4
1
ISBN(印刷版)9783037855171
DOI
出版ステータスPublished - 2013
イベント24th Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2012 - Fukuoka, Japan
継続期間: 2012 10月 212012 10月 24

出版物シリーズ

名前Key Engineering Materials
番号1
529-530
ISSN(印刷版)1013-9826
ISSN(電子版)1662-9795

Other

Other24th Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2012
国/地域Japan
CityFukuoka
Period12/10/2112/10/24

ASJC Scopus subject areas

  • 材料科学(全般)
  • 材料力学
  • 機械工学

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