Odobromoamide, a terminal alkynyl bromide-containing cyclodepsipeptide from the marine cyanobacterium okeania sp.

Kosuke Sueyoshi, Takafumi Kudo, Aki Yamano, Shimpei Sumimoto, Arihiro Iwasaki, Kiyotake Suenaga, Toshiaki Teruya

研究成果: Article査読

7 被引用数 (Scopus)

抄録

The bioassay-guided fractionation of the Okinawan marine cyanobacterium Okeania sp. led to the isolation of the novel cyclodepsipeptide odobromoamide (1). The gross structure of 1 was determined by spectroscopic analyses, and its absolute stereochemistry was determined using a variety of different methods, including chemical derivatization and degradation followed by HPLC analysis. In addition, odobromoamide (1) exhibited broad-spectrum cytotoxicity against a human cancer cell line panel.

本文言語English
ページ(範囲)436-440
ページ数5
ジャーナルBulletin of the Chemical Society of Japan
90
4
DOI
出版ステータスPublished - 2017

ASJC Scopus subject areas

  • Chemistry(all)

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