On the interplay of gene positioning and the role of rho-independent terminators in Escherichia coli

研究成果: Article査読

6 被引用数 (Scopus)

抄録

The majority of intrinsic rho-independent terminator signals, reported to consist of stable hairpin structures followed by T-rich regions, possess the potential to operate bi-directionally and to induce transcription terminations on both strands of the DNA duplex in Escherichia coli. By using RNAMotif software, we investigated the distributions of termination motifs around the 3′-ends of overlapping and non-overlapping genes at the genomic level. We suggest that the positions of compactly encoded E. coli genes and rho-independent terminators are optimized to terminate the adjoining genes on their antisense strands efficiently, and not to mis-terminate overlapping transcripts, due to their bi-directional properties.

本文言語English
ページ(範囲)6909-6914
ページ数6
ジャーナルFEBS Letters
580
30
DOI
出版ステータスPublished - 2006 12 22

ASJC Scopus subject areas

  • 生物理学
  • 構造生物学
  • 生化学
  • 分子生物学
  • 遺伝学
  • 細胞生物学

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