On the mechanism of gating defects caused by the R117H mutation in cystic fibrosis transmembrane conductance regulator

Medicine & Life Sciences

• Cystic Fibrosis Transmembrane Conductance Regulator 100%
• ivacaftor 44%
• Mutation 44%
• Nucleotides 26%
• Adenosine Triphosphate 25%
• Cystic Fibrosis 19%
• N-(4-pyridylcarbonylamino)-1,2,3,6-tetrahydropyridine 15%
• Nitrates 14%
• 2'-deoxyadenosine triphosphate 12%
• Chloride Channels 8%
• Loss of Function Mutation 7%
• Histidine 7%
• Regulator Genes 6%
• Hydrolysis 6%
• Arginine 6%
• Ions 5%