One-Step Fabrication of Multi-Functional Core-Shell Janus Microparticles for Theranostics Application

Mio Tsuchiya, Yuta Kurashina, Yun Jung Heo, Hiroaki Onoe

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

We present a one-step method to fabricate microparticles to detect substances and release drugs in our bodies. Our microparticles have two compartments and an outer shell. The two compartments (Janus cores) enable the encapsulation of different materials separately for diagnosis and therapy while the outer shell reduces the adhesion and protects the encapsulated materials. These multi-functional core-shell Janus microparticles are fabricated by simply ejecting pre-gel solutions into a calcium chloride solution under centrifugal gravity application and UV irradiation. Moreover, we implanted these microparticles in biological tissue and demonstrated the transdermal sensing and drug model release. We believe that our fabrication method and particle design could be an effective approach for multi-functional smart theranostic medicine.

本文言語English
ホスト出版物のタイトル33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020
出版社Institute of Electrical and Electronics Engineers Inc.
ページ32-35
ページ数4
ISBN(電子版)9781728135809
DOI
出版ステータスPublished - 2020 1
イベント33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020 - Vancouver, Canada
継続期間: 2020 1 182020 1 22

出版物シリーズ

名前Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
2020-January
ISSN(印刷版)1084-6999

Conference

Conference33rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2020
CountryCanada
CityVancouver
Period20/1/1820/1/22

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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