Optical coefficient measurements using bulk living tissue with optical fiber puncture

Haruna Nakazawa, Marika Doi, Emiyu Ogawa, Tsunenori Arai

研究成果: Article査読

抄録

Slicing sample preparation in tissue optical characteristic measurement may makes huge error over individual optical differences. We proposed the combination of light intensity measurement through an optical fiber puncturing into a bulk tissue varying detection numerical aperture and ray tracing calculation to avoid slicing degradation of living tissue. To reveal the characteristics of this measurement, optical coefficients of pig myocardium obtained by the IAD method with slicing living tissue sample preparation and proposed measurement method were compared. In the proposed method, a silica fiber installed in an18G needle was punctured up to the bottom of the myocardial bulk tissue to measure light intensity in the bulk tissue changing depth and numerical aperture. The author found that measured apparent attenuation coefficients tended to strongly depend on numerical aperture. The ray trace calculation explained the same numerical aperture tendency in above mentioned experimental result. Optical characteristics of sliced myocardial samples revealed temporal change due to dehydration.

本文言語English
ページ(範囲)597-598
ページ数2
ジャーナルTransactions of Japanese Society for Medical and Biological Engineering
55
Proc
DOI
出版ステータスPublished - 2017

ASJC Scopus subject areas

  • Biomedical Engineering

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