Optogenetics research using the mouse as a model system

研究成果: Chapter

抄録

Smooth progress in the field of optogenetic research can be, as the suffix ‘-genetics’ indicates, expected using biological models that provide conditions suitable for genetic control or gene manipulation. The artificial expression of opsin molecules is expected to be carried out smoothly in mice compared with rats or non-human primates because of established inheritable genetic modification technologies in this species. However, when compared with the nematode or the fly, there are still many difficulties in the expression of opsin in mice if flexible gene manipulation is attempted.

本文言語English
ホスト出版物のタイトルOptogenetics
ホスト出版物のサブタイトルLight-Sensing Proteins and their Applications
出版社Springer Japan
ページ227-240
ページ数14
ISBN(電子版)9784431555162
ISBN(印刷版)9784431555155
DOI
出版ステータスPublished - 2015 1月 1

ASJC Scopus subject areas

  • 医学(全般)
  • 神経科学(全般)
  • 生化学、遺伝学、分子生物学(全般)

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