Oxidative Kinetic Resolution of Acyclic Amines Based on Equilibrium Control

Kodai Saito, Hiromitsu Miyashita, Yui Ito, Masahiro Yamanaka, Takahiko Akiyama

研究成果: Article査読

3 被引用数 (Scopus)

抄録

An oxidative kinetic resolution of racemic acyclic amines was developed using an imine derivative as the resolving reagent and chiral phosphoric acid as the catalyst to give enantiomers in good yields with high to excellent enantioselectivities. The key to success of the title reaction was the equilibrium control by adjusting the ratio of the resolving reagent, and unique enantiodivergence was observed depending on the equilibrium displacement.

本文言語English
ページ(範囲)3128-3134
ページ数7
ジャーナルOrganic Letters
22
8
DOI
出版ステータスPublished - 2020 4 17

ASJC Scopus subject areas

  • 生化学
  • 物理化学および理論化学
  • 有機化学

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