Pancreas duct abnormalities in patients with ulcerative colitis: A magnetic resonance pancreatography study

Nobuo Toda, Masaaki Akahane, Shigeru Kiryu, Yasuo Matsubara, Yutaka Yamaji, Makoto Okamoto, Nobuyuki Minagawa, Kazuyuki Ohgi, Yutaka Komatsu, Naohisa Yahagi, Haruhiko Yoshida, Takao Kawabe, Kuni Ohtomo, Masao Omata

研究成果: Article査読

19 被引用数 (Scopus)

抄録

Background: The presumed etiology and prevalence of pancreatic abnormalities in patients with ulcerative colitis (UC) have been controversial. We conducted a controlled (cross-sectional) study of patients with UC compared with non-UC controls to determine the prevalence of pancreatic duct abnormalities in patients with UC and to determine if these are specific to UC using magnetic resonance cholangiopancreatography. Methods: Magnetic resonance cholangiopancreatography was performed on 79 unselected patients with UC and 45 non-UC controls, without a history of pancreatitis attack, between February 2000 and May 2003. Results: Among patients with UC, the prevalence of pancreatic duct abnormalities was 16.4% (95% confidence interval, 8.3%-24.6%): coexisting dilatation and narrowing of the main pancreatic duct were found in 5; diffuse narrowing of pancreatic ducts in 5; and dilatation of pancreatic ductal branches in 3. These abnormalities were compatible with chronic pancreatitis. Among the controls, no pancreatic duct abnormality was found. Conclusions: Changes in the pancreatic duct were found in approximately one-sixth of patients with UC, none of whom had a history of overt pancreatitis. These pancreatic duct abnormalities are likely to be specific to patients with UC.

本文言語English
ページ(範囲)903-908
ページ数6
ジャーナルInflammatory bowel diseases
11
10
DOI
出版ステータスPublished - 2005 10 1
外部発表はい

ASJC Scopus subject areas

  • Immunology and Allergy
  • Gastroenterology

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