Papillary adenoma of the distal common bile duct

Mitsuhiro Inagaki, Akira Ishizaki, Shuichi Kino, Kazuhiko Onodera, Kakuya Matsumoto, Kazunori Yokoyama, Isao Makino, Hidenori Ojima, Yoshihiko Tokusashi, Naoyuki Miyokawa, Shinichi Kasai

研究成果: Article査読

8 被引用数 (Scopus)


A 73-year-old man with a papillary adenoma located in the distal common bile duct is reported. He underwent pylorus-preserving pancreatoduodenectomy. The lesion in the common bile duct featured papillary proliferation of the epithelium and fibrous elements with diffuse infiltration by inflammatory cells. Positive staining for MIB-1 (Ki-67) and p53 was identified in the nuclei of the proliferative epithelium. These findings suggested the malignant potential of this lesion. Further progress in imaging diagnostic techniques should increase the frequency with which such lesions are discovered. Even now, if mural irregularities and defects are found in the extrahepatic biliary system, especially the distal common bile duct, the possibility of such borderline biliary adenoma should be taken into consideration when making a diagnosis.

ジャーナルJournal of gastroenterology
出版ステータスPublished - 1999 8 1

ASJC Scopus subject areas

  • Gastroenterology

フィンガープリント 「Papillary adenoma of the distal common bile duct」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。