Paradoxical increases in serum levels of highly chlorinated PCBs in aged women in clear contrast to robust decreases in dietary intakes from 1980 to 2003 in Japan

Akio Koizumi, Kouji H. Harada, Bita Eslami, Yoshinori Fujimine, Noriyuki Hachiya, Iwao Hirosawa, Kayoko Inoue, Sumiko Inoue, Shigeki Koda, Yukinori Kusaka, Katsuyuki Murata, Kazuyuki Omae, Norimitsu Saito, Shinichiro Shimbo, Katsunobu Takenaka, Tatsuya Takeshita, Hidemi Todoriki, Yasuhiko Wada, Takao Watanabe, Masayuki Ikeda

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Objective Exposure to polychlorinated biphenyls (PCBs) is considered to have culminated between 1950 and 1970 in Japan, and exposure through diet, the major exposure route, has decreased significantly over the last 10 years. The primary goal of the present study was to investigate the long-term trends and congener profiles of serum and dietary levels of PCBs using historical samples. Methods Using banked samples collected in 1980, 1995, and 2003 surveys, we determined the daily intakes and serum concentrations of 13 PCB congeners (#74, #99, #118, #138, #146, #153, #156, #163, #164, #170, #180, #182, and #187) in women. Results The total daily PCB intake [ng/day, geometric mean (geometric standard deviation)] decreased signifi- cantly from 523 (2.5) in 1980 to 63 (3.2) in 2003.

本文言語English
ページ(範囲)235-246
ページ数12
ジャーナルEnvironmental Health and Preventive Medicine
14
4
DOI
出版ステータスPublished - 2009 7

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

フィンガープリント 「Paradoxical increases in serum levels of highly chlorinated PCBs in aged women in clear contrast to robust decreases in dietary intakes from 1980 to 2003 in Japan」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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