Parallel recognition of single-stranded DNA using a biological nanopore array

Y. Tsuji, R. Kawano, T. Osaki, H. Sasaki, N. Miki, S. Takeuchi

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

This paper describes simultaneous detections of a single DNA molecule using a biological nanopore in an array device (Figure 1a). In the previous report, we have successfully reconstituted α-hemolysin αHL) in bilayer lipid membranes (BLMs) using droplets contacting method[1]. In this research, we attempted to detect single-stranded DNA (ssDNA) translocation events through the protein channel. As a result, we succeeded in observing ssDNA translocation events in 15ch simultaneously. We believe that this method can be applied to an automated and high-throughput DNA analysis.

本文言語English
ホスト出版物のタイトル15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
ページ1284-1286
ページ数3
出版ステータスPublished - 2011
イベント15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
継続期間: 2011 10 22011 10 6

出版物シリーズ

名前15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
2

Other

Other15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
国/地域United States
CitySeattle, WA
Period11/10/211/10/6

ASJC Scopus subject areas

  • 制御およびシステム工学

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