Parametric study for laser hot balloon angioplasty to suppress chronic restenosis: animal experiment

Tsunenori M.D. Arai, Takayuki Miyake, Masami Sakurada, Akira M.D. Miyamoto, Kyoichi M.D. Mizuno, Makoto Kikuchi, Haruo M.D. Nakamura, Atsushi Utsumi, Kiyoshi Takeuchi

研究成果: Conference contribution

12 被引用数 (Scopus)

抄録

To suppress restenosis after the percutaneous transluminal coronary angioplasty (PTCA), we experimentally investigated the optimum parameter setting on the combination of the balloon temperature and heating duration of our laser hot balloon catheter in rabbit model. The rabbit femoral arteries were treated by our laser hot balloon of 2.5 mm in diameter with various balloon temperatures and durations at the range from 60 to 90 deg., and from 15 to 30 seconds, respectively. The histological examination showed that high temperature (greater than 70 deg.) was necessary to suppress hyperplasia of the vessel in chronic phase. The angiography of pre- and post-treatment and of 2 months after the treatment showed that high temperature with short heating duration (15-30 s) was the best setting for chronic patency of the treated vessels. The laser hot balloon angioplasty with the above mentioned parameter setting might realize significant improvement on chronic patency after PTCA.

本文言語English
ホスト出版物のタイトルProceedings of SPIE - The International Society for Optical Engineering
編集者R.Rox Anderson
ページ36-39
ページ数4
出版ステータスPublished - 1996 1 1
イベントLasers in Surgery: Advanced Characterization, Therapeutics, and Systems VI - San Jose, CA, USA
継続期間: 1996 1 271996 1 30

出版物シリーズ

名前Proceedings of SPIE - The International Society for Optical Engineering
2671

Other

OtherLasers in Surgery: Advanced Characterization, Therapeutics, and Systems VI
CitySan Jose, CA, USA
Period96/1/2796/1/30

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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