Partition coefficients of polyphenols for phosphatidylcholine investigated by HPLC with an immobilized artificial membrane column

Yoshinori Uekusa; Yuko Takeshita; Takeshi Ishii; Tsutomu Nakayama

doi:10.1271/bbb.80435

Partition coefficients of polyphenols for phosphatidylcholine investigated by HPLC with an immobilized artificial membrane column

Yoshinori Uekusa, Yuko Takeshita, Takeshi Ishii, Tsutomu Nakayama

研究成果: Article › 査読

16 被引用数 (Scopus)

抄録

The biological activity of polyphenols in vitro reflects their affinity for cell membranes and the amount of cellular incorporation. The interaction of polyphenols with phosphatidylcholine was investigated by HPLC with an immobilized artificial membrane (IAM) column. The IAM partition coefficients (K_IAM) of the polyphenols, calculated by retention times, correlated well with the amounts of polyphenols incorporation into the liposomes.

本文言語	English
ページ（範囲）	3289-3292
ページ数	4
ジャーナル	Bioscience, Biotechnology and Biochemistry
巻	72
号	12
DOI	https://doi.org/10.1271/bbb.80435
出版ステータス	Published - 2008
外部発表	はい

ASJC Scopus subject areas

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

文献へのアクセス

10.1271/bbb.80435

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引用スタイル

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title = "Partition coefficients of polyphenols for phosphatidylcholine investigated by HPLC with an immobilized artificial membrane column",

abstract = "The biological activity of polyphenols in vitro reflects their affinity for cell membranes and the amount of cellular incorporation. The interaction of polyphenols with phosphatidylcholine was investigated by HPLC with an immobilized artificial membrane (IAM) column. The IAM partition coefficients (KIAM) of the polyphenols, calculated by retention times, correlated well with the amounts of polyphenols incorporation into the liposomes.",

keywords = "HPLC, IAM partition coefficient (K), Immobilized artificial membrane (IAM), Lipid membranes, Polyphenol",

author = "Yoshinori Uekusa and Yuko Takeshita and Takeshi Ishii and Tsutomu Nakayama",

note = "Funding Information: This work was supported by a Grant-in-Aid, no. 19580147, for Scientific Research and by the Global COE Program of the Ministry of Education, Culture, Sports, Science, and Technology of Japan, and by a Sasakawa Scientific Research Grant from the Japan Science Society.",

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doi = "10.1271/bbb.80435",

language = "English",

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T1 - Partition coefficients of polyphenols for phosphatidylcholine investigated by HPLC with an immobilized artificial membrane column

AU - Uekusa, Yoshinori

AU - Takeshita, Yuko

AU - Ishii, Takeshi

AU - Nakayama, Tsutomu

N1 - Funding Information: This work was supported by a Grant-in-Aid, no. 19580147, for Scientific Research and by the Global COE Program of the Ministry of Education, Culture, Sports, Science, and Technology of Japan, and by a Sasakawa Scientific Research Grant from the Japan Science Society.

PY - 2008

Y1 - 2008

N2 - The biological activity of polyphenols in vitro reflects their affinity for cell membranes and the amount of cellular incorporation. The interaction of polyphenols with phosphatidylcholine was investigated by HPLC with an immobilized artificial membrane (IAM) column. The IAM partition coefficients (KIAM) of the polyphenols, calculated by retention times, correlated well with the amounts of polyphenols incorporation into the liposomes.

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KW - HPLC

KW - IAM partition coefficient (K)

KW - Immobilized artificial membrane (IAM)

KW - Lipid membranes

KW - Polyphenol

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