Path-length correction for the haemoglobin-concentration measurement using the skull cranial window by multi-spectral imaging analysis

Koichiro Sakaguchi, Shunsuke Furukawa, Takushige Katsura, Kyoko Yamazaki, Hideo Kawaguchi, Atsushi Maki, Eiji Okada

    研究成果: Conference contribution

    抄録

    The concentration changes in oxygenated haemoglobin and deoxygenated haemoglobin in the brain cortex of guinea pigs associated with brain activation are measured from the multi-spectral images of the cortical tissue. The cortical tissue is observed through a thinned skull. The wavelength dependence of the optical path length is considered in the calculation of haemoglobin concentration. The results are compared with those obtained from the multi-spectral images of the exposed cortex to evaluate the influence of the thinned skull on the measurement of the concentration changes by multi-spectral imaging system. Although the skull thickness affected the sensitivity of the change in reflectance due to decrease in optical path in the cortical tissue, the influence of skull on the wavelength dependence of the optical path length can be ignored when the skull thickness is approximately less than 100 μm.

    本文言語English
    ホスト出版物のタイトルDiffuse Optical Imaging of Tissue
    出版ステータスPublished - 2007 11 26
    イベントDiffuse Optical Imaging of Tissue - Munich, Germany
    継続期間: 2007 6 192007 6 21

    出版物シリーズ

    名前Progress in Biomedical Optics and Imaging - Proceedings of SPIE
    6629
    ISSN(印刷版)1605-7422

    Other

    OtherDiffuse Optical Imaging of Tissue
    CountryGermany
    CityMunich
    Period07/6/1907/6/21

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Biomaterials
    • Atomic and Molecular Physics, and Optics
    • Radiology Nuclear Medicine and imaging

    フィンガープリント 「Path-length correction for the haemoglobin-concentration measurement using the skull cranial window by multi-spectral imaging analysis」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

    引用スタイル