Periosteal Reaction Possibly Induced by Pazopanib: A Case Report and Literature Review

Takahiro Hosokawa, Tomoko Hara, Yuki Arakawa, Eiji Oguma, Yoshitake Yamada

研究成果: Article査読

3 被引用数 (Scopus)

抄録

Background:Although complications associated with pazopanib, a multitarget tyrosine kinase inhibitor, are known, periosteal reaction as a side effect has never been reported.Observation:We present a case involving a male pediatric patient with desmoid tumors treated for 6 months with pazopanib who presented with pain and periosteal reaction in the ilium and scapula. Three months after termination of pazopanib therapy, the periosteal reaction in the scapula resolved and that in the ilium improved.Conclusion:Children receiving pazopanib presenting with focal pain should be examined for the periosteal reaction; this knowledge may facilitate correct diagnosis of symptoms as a drug-associated finding.

本文言語English
ページ(範囲)e822-e825
ジャーナルJournal of Pediatric Hematology/Oncology
42
8
DOI
出版ステータスPublished - 2020 11 1

ASJC Scopus subject areas

  • 小児科学、周産期医学および子どもの健康
  • 血液学
  • 腫瘍学

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