Permuted tRNA genes expressed via a circular RNA intermediate in Cyanidioschyzon merolae

Akiko Soma, Akinori Onodera, Junichi Sugahara, Akio Kanai, Nozomu Yachie, Masaru Tomita, Fujio Kawamura, Yasuhiko Sekine

研究成果: Article査読

75 被引用数 (Scopus)

抄録

A computational analysis of the nuclear genome of a red alga, Cyanidioschyzon merolae, identified 11 transfer RNA (tRNA) genes in which the 3′ half of the tRNA lies upstream of the 5′ half in the genome. We verified that these genes are expressed and produce mature tRNAs that are aminoacylated. Analysis of tRNA-processing intermediates for these genes indicates an unusual processing pathway in which the termini of the tRNA precursor are ligated, resulting in formation of a characteristic circular RNA intermediate that is then processed at the acceptor stem to generate the correct termini.

本文言語English
ページ(範囲)450-453
ページ数4
ジャーナルScience
318
5849
DOI
出版ステータスPublished - 2007 10 19

ASJC Scopus subject areas

  • General

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