Pharmacology of acute lung injury

Sadatomo Tasaka, Naoki Hasegawa, Akitoshi Ishizaka

研究成果: Review article査読

48 被引用数 (Scopus)

抄録

The acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a clinical syndrome that affects both medical and surgical patients. To date, despite improved understanding of the pathogenesis of ALI/ARDS, pharmacological modalities have been unsuccessful in decreasing mortality. However, several pharmacological agents for ARDS are in development and have shown great promise. In addition to the anti-inflammatory category including late corticosteroids, inhaled nitric oxide, alveolar surfactant, and vasodilators are being evaluated. Replacements of anticoagulation mediators have also suggested beneficial effects on the patient outcome. This article provides an overview of pharmacological treatments of ALI/ARDS.

本文言語English
ページ(範囲)83-95
ページ数13
ジャーナルPulmonary Pharmacology and Therapeutics
15
2
DOI
出版ステータスPublished - 2002 1 1

ASJC Scopus subject areas

  • 呼吸器内科
  • 生化学、医学
  • 薬理学(医学)

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