Phosphorylation of a new member of the bicarbonate cotransporter superfamily

M. Hayashi

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Acid-base balance is regulated by cortical collecting duct cells in kidney, where the transporter functions of β-intercalated cells are controlled by such factors as isoproterenol, cyclic adenosine monophosphate (cAMP), and the protein kinase A (PKA) pathway. The apical anion exchanger (AE) in β-intercalated cells is thought to be involved in the secretion of bicarbonate into urine. In isolated cells, the Cl- channel was shown to be activated by isoproterenol via the PKA pathway. The importance of the PKA pathway and phosphorylation in the regulation of its transporter activity is not yet known.

本文言語English
ページ(範囲)462-465
ページ数4
ジャーナルKidney international
60
2
DOI
出版ステータスPublished - 2001
外部発表はい

ASJC Scopus subject areas

  • 腎臓病学

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