Pilot study on sentinel node biopsy in breast cancer

Shigeru Imoto, Hiroyoshi Fukukita, Kohji Murakami, Hiroshi Ikeda, Noriyuki Moriyama

研究成果: Article

38 引用 (Scopus)

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Background and Objectives: Sentinel node biopsy (SNB) in breast cancer using indigo carmine was started in January 1998, and this method has proved feasible and reliable. From our initial experience, sentinel lymph nodes (SLNs) were identified in 65 of 88 cases of breast cancer (74%). Methods: Lymphatic mapping in breast cancer was assessed using radionuclide, technetium-99m human serum albumin or technetium-99m tin colloid. A pilot study on SNB with dye or a combined method was performed between August 1998 and January 1999. Results: SLNs were identified in 55 of 59 cases (93%). False-negative SLNs were found in 2 cases. The sensitivity and accuracy in all cases were 92% and 96%. SLNs in 52 cases were also diagnosed by immediate frozen sectioning. The sensitivity and accuracy were 89% and 96%. Conclusions: SNB in the combined method was the best way to identify SLNs in breast cancer. (C) 2000 Wiley-Liss, Inc.

元の言語English
ページ(範囲)130-133
ページ数4
ジャーナルJournal of Surgical Oncology
73
発行部数3
DOI
出版物ステータスPublished - 2000 4 7

ASJC Scopus subject areas

  • Surgery
  • Oncology

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